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Unlike the adult trial, where the primary endpoint was the change of trunk fat mass from baseline at 26 weeks, the primary endpoint in the pediatric trial is annual height velocity after 12 months of treatment. HGH CTP demonstrated strong results in the phase 2 trial which should be replicated in the phase 3 trial. HGH CTP performed well even in the phase 3 trial in adults, but according to OPKO, the outliers in the placebo group affected the results.

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