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In a phase 2 trial, TransCon hGH has shown comparable efficacy to once daily Genotropin. The height velocity (HV) TransCon hGH achieved was in the 11.9cm to 13.9cm range compared to 11.6cm for Genotropin. Too little is not good as children won't grow to reach their targeted height, and too much hGH can lead to another condition acromegaly, which leads to tissue overgrowth, diabetes, heart disease, stroke and poor quality of life.It is also important to monitor IGF 1, or insulin like growth factor 1.

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